• Question: In the hydrogencarbonate buffer in blood, why is there no conjugate base? Surely this means that the pH cannot be increased?

    Asked by eigenvector to Arttu, Ceri, James_M, Monica, Philip on 21 Jun 2011.
    • Photo: James M Monk

      James M Monk answered on 21 Jun 2011:


      I’m by no means an expert on this, but from my A level chemistry all those years ago I seem to remember that a buffered solution contained a compound that would stabilise the pH of a solution by freeing up or binding hydrogen ions. Clearly it is very important that blood stays at the right pH, so I don’t find it at all surprising that blood contains such buffering compounds.

      I’m sorry I don’t know more about this subject – it sounds quite interesting.

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